If Quins think they have something to prove after last week's exit from the European Championship Cup they could ask for no bigger opportuinity than to take on the league leaders.
Leicester Tigers arrive with 80 points already in the bag - some 12 points ahead of Quins who need the win to consoldiate their place in the top four.
It's undoubtedly the game of the weekend with two contrasting styles on show - Quins' flair versues Tigers organisation and strength. Intriguing to say the least.
Quins make just two changes with skipper Stephan Lewis returning to lead from the front and Luke Wallace in for the injured Will Evans.
On the bench the squad will be bolstered by the return of James Chisholm and Tom Lawday.
The game will be dedicted to former Harlequin Seb Adeniran–Olule and "Seb’s Foundation" - run by his mother following his tragic death in 2016.
Quins: 1. Joe Marler 2. Jack Walker 3. Will Collier 4. Matt Symons 5. Hugh Tizard 6. Stephan Lewies (capt) 7. Luke Wallace 8. Alex Dombrandt 9. Danny Care 10. Marcus Smith 11. Cadan Murley 12. Andre Esterhuizen 13. Joe Marchant 14. Louis Lynagh 15. Huw Jones.
Bench: 16. Joe Gray 17. Simon Kerrod 18. Wilco Louw 19. George Hammond 20. James Chisholm 21. Tom Lawday 22. Lewis Gjaltema 23. Nick David
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