Last week's 3-0 demolition of local rivals Wigan Athletic will have done the second string the power of good and coach Jimmy Phillips will be looking for his side to repeat such a performance and move off the foot of the table.
Once again Phillips will have a strong side at his disposal with a number of first team players on show including El-Hadji Diouf, Henrik Pedersen, Jared Borgetti, Hidetoshi Nakata and Ivan Campo.
Boro include former Derby striker Malcolm Christie in their side and there is also a place for veteran defender Colin Cooper, who celebrated his 39th birthday a couple of months ago.
Earlier on in the season a second half goal from defender Bradley Hill wasn't enough as Boro ran out comfortable 3-1 winners at the County Ground.
Bolton Wanderers Reserves: Ali Al-Habsi, Nicky Hunt, Henrik Pedersen, Mark Charlesworth, Jarostaw Fojut, Hidetoshi Nakata, El-Hadji Diouf, Ivan Campo, Jared Borgetti, Ricardo Vaz-Te, Matt Jansen
Subs From: Oscar Perez, Przemyslaw Kazimerczak, Robert Sissons, Blazej Augustyn, Johann Smith
Middlesbrough Reserves: Brad Jones, John Johnson, Jonathan Grounds, Josh Walker, Matthew Bates, Colin Cooper, Nathan Fisher, Jason Kennedy, Malcolm Christie, Tom Craddock, Adam Johnson
Subs From: illiams, David Knight, Robson, Richard Langthorne, Stephen Thompson
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